Rosacea chirwere chinowanzoonekwa nekutsvuka kwechiso uye kuzvimba.Inobata nezve 5% yehuwandu hwepasi rose, uye kunyangwe zvikonzero zvichizivikanwa, hazvizivikanwe zvakanyanya.Inofungidzirwa seganda renguva refu, uye rinowanzobata vakadzi veEurope / Caucasian pamusoro pemakore makumi matatu.
Red light therapy inodzidzwa zvakanaka kune zvinhu zvakaita sekuporesa kweganda, kuzvimba kazhinji, collagen paganda, uye akasiyana ane hukama mamiriro eganda senge acne.Sezvineiwo kufarira kwakakura mukushandisa mwenje dzvuku ye rosacea.Muchikamu chino tichatarisa kana kwete red light therapy (inozivikanwawo se photobiomodulation, LED therapy, laser therapy, cold laser, light therapy, LLLT, nezvimwewo) inogona kubatsira kurapa rosacea.
Mhando dzeRosacea
Munhu wese ane rosacea ane zviratidzo zvakasiyana uye zvakasiyana.Kunyange zvazvo rosacea inowanzobatanidzwa nekutsvuka kwechiso kwakakomberedza mhino nematama, pane zvimwe zvakasiyana-siyana zviratidzo zvinogona kuputsika uye kuiswa mu rosacea 'subtypes':
Subtype 1, inodaidzwa se 'Erythematotelangiectatic Rosacea' (ETR), ndiyo stereotypical rosacea inoburitsa nekutsvuka kwechiso, kuzvimba kweganda, tsinga dzeropa dziri pedyo nepamusoro uye nguva dzekutsvaira.Erythema inobva pashoko rechiGiriki rokuti erythros, rinoreva tsvuku - uye rinoreva ganda dzvuku.
Subtype 2, Acne rosacea (zita resainzi - papulopustular), irosacea apo ganda dzvuku rinosanganiswa nekuramba kana kupindira kwebundu-kunge kuputika (pustules nemapules, kwete matema).Rudzi urwu runogona kukonzera kutsva kana kuruma.
Subtype 3, AKA phymatous rosacea kana rhinophyma, imhando isingawanikwe yerosacea uye inosanganisira zvikamu zvechiso zvichiwedzera kukura - kazhinji mhuno (mbatatisi mhuno).Inonyanyozivikanwa muvarume vakuru uye inowanzotanga seimwe subtype ye rosacea.
Subtype 4 is rosacea yeziso, kana ocular rosacea, uye inosanganisira maziso akatsvuka, maziso ane mvura, kunzwa kwechimwe chinhu muziso, kupisa, kuputika uye kuputika.
Kuziva nezve subtypes ye rosacea kwakakosha pakuona kuti iwe unayo here.Kana pasina chaitwa kugadzirisa rosacea, inowanzowedzera kuipa nekufamba kwenguva.Sezvineiwo, kushanda kwered light therapy kurapa rosacea hakuchinji neiyo subtype.Zvichireva iyo yakafanana red light therapy protocol yaizoshanda kune ese madiki.Sei?Ngatitarisei zvikonzero zve rosacea.
Chikonzero Chaicho cheRosacea
(... uye nei kurapwa kwechiedza kunogona kubatsira)
Makumi emakore anoverengeka apfuura, rosacea yakatanga kutenda semhedzisiro yehutachiona hwehutachiona.Sezvo mishonga inorwisa mabhakitiriya (kusanganisira tetracycline) yakashanda kusvika padanho rekugadzirisa zviratidzo, zvaiita sedzidziso yakanaka….asi nekukasira zvakaonekwa kuti pakanga pasina utachiona.
Vanachiremba vazhinji uye nyanzvi dze rosacea mazuva ano vachakuudza kuti rosacea ine enigmatic uye hapana akawana chikonzero.Vamwe vachanongedzera kuDemodex mite sechikonzero, asi anenge munhu wese ane izvi uye kwete munhu wese ane rosacea.
Ipapo ivo vanozonyora zvakasiyana-siyana 'zvinokonzeresa' panzvimbo yechikonzero, kana kuita mazano ayo asina kutaurwa genetics uye zvakatipoteredza zvinhu ndizvo zvakakonzera.Kunyange zvazvo genetic kana epigenetic zvinhu zvinogona kutungamirira mumwe munhu kuti awane rosacea (hama kune mumwe munhu), havazvizivi - haisi iyo chikonzero.
Zvinhu zvakasiyana-siyana zvinopa kuoma kwezviratidzo zverosacea (caffeine, zvinonhuhwirira, zvimwe zvekudya, kutonhora/kupisa mamiriro ekunze, kushushikana, doro, nezvimwewo), asi ivowo handizvo zvakakonzera.
Saka chii?
Mazano kune chikonzero
Chiratidzo chekutanga chechikonzero chiri mukuti rosacea inowanzokura mushure memakore 30. Iyi ndiyo nguva apo zviratidzo zvekutanga zvekukwegura zvinobuda pachena.Vanhu vazhinji vanozoona bvudzi ravo rekutanga grey uye yekutanga ganda diki kuunyana mukati mezera rino.
Imwe pfungwa inyaya yekuti mishonga inorwisa mabhakitiriya inobatsira kugadzirisa zviratidzo - kunyangwe pasina hutachiona chaihwo (kunongedza: maantibiotic anogona kuva nemhedzisiro yenguva pfupi yekurwisa-kuzvimba).
Ropa rinoyerera kune ganda rinobatwa ne rosacea rinenge 3 kusvika 4 nguva yakakwirira kupfuura kune ganda rakajairika.Iyi hyperemia mhedzisiro inoitika kana matishu uye masero asingakwanisi kuburitsa okisijeni kubva muropa.
Isu tinoziva kuti rosacea haingori nyaya yekushongedza chete, asi inosanganisira yakakosha shanduko yekukura kwefibrotic paganda (saka mhino yembatatisi mune subtype 3) uye inovharisa tsinga yeropa kukura (nekudaro tsinga/flushing).Kana izvi zviratidzo zvakafanana zvikaitika kune imwe nzvimbo mumuviri (semuenzaniso uterine fibroids) zvinoda kuongororwa kwakakosha, asi muganda vanorambwa senyaya dzekuzora dzinofanirwa 'kugadziriswa' ne'kudzivisa zvinokonzeresa', uye gare gare kunyange kuvhiyiwa kubvisa ganda rakakora. .
Rosacea inyaya yakakosha nekuti chisakiso inzira yemuviri yakadzika mumuviri.Mamiriro emuviri anotungamira kukuchinja kweganda uku haasi kukanganisa ganda chete - anokanganisa muviri wese wemukati zvakare.
Kuputika, kukura / kupindira kwemidziyo yeropa uye kuwedzera kweganda kunogona kuonekwa nyore nyore mu rosacea, nokuti inoratidzika muganda - pamusoro pemuviri.Nenzira, chikomborero kuwana zviratidzo zverosacea, nokuti zvinokuratidza kuti chimwe chinhu chisina kunaka mukati.Kurasika kwebvudzi revarume chinhu chakafanana pakuti kunongedza kune kukonzeresa kukanganiswa kwehomoni.
Mitochondrial defects
Zvese zvekutarisa uye zviyero zvine chekuita nerosacea zvinonongedza kumatambudziko emitochondrial sechikonzero chinokonzera rosacea.
Mitochondria haigoni kushandisa oxygen zvakanaka kana yakuvadzwa.Kusakwanisa kushandisa okisijeni kunowedzera kuyerera kweropa kune imwe tishu.
Mitochondria inogadzira lactic acid kana isingakwanise kuwana uye kushandisa okisijeni, izvo zvinotungamira kune vasodilation nekukurumidza uye kukura kwefibroblasts.Kana dambudziko iri rakareba kwenguva yakareba, mitsva yeropa inotanga kukura.
Zvakasiyana-siyana zvehomoni uye zvakatipoteredza zvinogona kuita kuti mitochondrial isashande zvakanaka, asi mumamiriro ekurapa mwenje tsvuku, kukosha kwakanyanya kunobva kumorekuru rinonzi Nitric Oxide.
Red Light Therapy uye Rosacea
Dzidziso huru inotsanangura mwenje mhedzisiro yekurapa yakavakirwa pamorekuru rinonzi Nitric Oxide (NO).
Iyi imorekuru inogona kuva nemigumisiro yakasiyana-siyana pamuviri, yakadai sekudzivirira simba rekugadzira, vasodilation / kuwedzera kwemidziyo yeropa, nezvimwewo.Iyo yatinonyanya kufarira yekurapa mwenje ndeyekuti iyi HAPANA inosunga panzvimbo yakakosha mune yako mitochondrial electron cheni yekufambisa, ichimisa kuyerera kwesimba.
Inovharira nhanho dzekupedzisira dzekufema, saka inokumisa iwe kuwana iyo huru chunk yesimba (ATP) uye chero kabhoni dhaibhorosi kubva kuglucose/okisijeni.Saka kana vanhu vaine akadzikira zvachose metabolic mazinga pavanenge vachichembera kana kusangana nenguva yekushushikana / nzara, iyi NO inowanzoita basa.Izvo zvine musoro kana iwe uchifunga nezvazvo, muzvisikwa kana mukupona, iwe unoda michina yekudzikisa yako metabolic rate munguva dzekudzikira chikafu / calorie kuwanikwa.Hazvina musoro zvikuru munyika yanhasi umo NO mazinga anogona kufurirwa neakananga mhando amino acids muzvokudya, kusvibiswa mhepo, chakuvhe, zvimwe zvokudya zvinhu, chakagadzirwa chiedza, etc. Kushaikwa carbon dioxide mumuviri wedu zvakare. kunowedzera kuzvimba.
Kurapa kwechiedza kunowedzera kugadzirwa kwezvose simba (ATP) uye carbon dioxide (CO2).Iyo CO2 inodzivisa akasiyana-siyana e-pro-inflammatory cytokines uye prostaglandin.Saka kurapwa kwakareruka kunoderedza kuwanda kwekuzvimba mumuviri/nzvimbo.
Kune rosacea chinhu chakakosha chekutora ndechekuti kurapwa kwakareruka kunoderedza kuzvimba nekutsvuka munzvimbo, uye zvakare kugadzirisa dambudziko rekushomeka kweokisijeni kushandiswa (izvo zvakakonzera kukura kwetsinga yeropa uye kukura kwefibroblast).
Summary
Kune akasiyana subtypes uye kuratidzwa kwe rosacea
Rosacea chiratidzo chekuchembera, semakwinya uye bvudzi jena
Chikonzero cherosacea chakaderedzwa basa remitochondrial mumasero
Red light therapy inodzorera mitochondria uye inoderedza kuzvimba, kudzivirira rosacea
Nguva yekutumira: Sep-30-2022